Gastroesophageal reflux disease (GERD)

Gastroesophageal reflux disease (GERD) is a chronic condition in which stomach acid repeatedly flows back up into the esophagus, the tube connecting your mouth and stomach. This backwash can irritate the lining of the esophagus and cause uncomfortable symptoms. It's more than just occasional heartburn; GERD is a persistent condition that requires proper management. 

Signs and symptoms

The symptoms of GERD can vary widely among individuals, but the most common ones are heartburn and regurgitation. 

Common symptoms include:

  • Heartburn: A burning sensation in the chest that often occurs after eating and may worsen at night or while lying down.

  • Regurgitation: The backwash of sour liquid or stomach contents into your throat or mouth (esophagitis with acid brash).

  • Chest pain: A non-burning chest pain that should be evaluated by a doctor to rule out more serious issues like a heart attack.

  • Difficulty swallowing (dysphagia): The sensation of food being stuck in your throat.

  • Sensation of a lump in the throat (globus sensation): The feeling that something is caught in your throat.

  • A bitter or sour taste in your mouth (acid brash)

Other, less common symptoms can include:

  • A persistent dry cough

  • Hoarseness or a sore throat

  • Nausea

  • Trouble sleeping due to symptoms

  • Worsening asthma 

Diagnosis

In many cases, a doctor can diagnose GERD based on your symptoms alone and your response to lifestyle changes and medication. You might not need specific diagnostic testing unless your symptoms are severe, don't improve with initial treatment, or you have "alarm symptoms" such as difficulty swallowing, bleeding, or unexplained weight loss. 

If further testing is needed, a doctor may recommend:

  • Upper endoscopy: A thin, flexible tube with a camera is inserted down your throat to view the esophagus and stomach. This can check for inflammation, ulcers, or other complications and may involve a biopsy (taking a small tissue sample).

  • pH monitoring: A test that measures the amount of acid in your esophagus over a 24- to 48-hour period. A wireless capsule or a thin catheter can be used to track acid levels and correlate them with your symptoms.

  • Esophageal manometry: This test measures the pressure and movement of the esophageal muscles to see if they are working correctly. It is often used to rule out other conditions and may be helpful if you are considering surgery. 

Treatment

Treatment for GERD usually begins with lifestyle changes and progresses to medication or, in severe cases, surgery if symptoms persist. 

Lifestyle and home remedies:

  • Maintain a healthy weight: Excess weight puts pressure on your abdomen and stomach, which can force acid into your esophagus.

  • Avoid trigger foods and drinks: Common culprits include fatty foods, spicy foods, chocolate, caffeine, alcohol, and acidic foods like citrus and tomatoes.

  • Eat smaller, more frequent meals: Large meals can increase pressure on your stomach.

  • Do not lie down after eating: Wait at least three hours after a meal before lying down or going to bed.

  • Elevate the head of your bed: Raising the head of your bed by 6 to 8 inches can help gravity keep stomach acid down. Using extra pillows is not effective.

  • Quit smoking: Smoking weakens the lower esophageal sphincter, the muscle that keeps acid from backing up into the esophagus.

  • Wear loose-fitting clothing: Tight clothing can put extra pressure on your abdomen. 

Medication:

  • Antacids: Over-the-counter options like Tums, Rolaids, and Maalox provide quick but temporary relief by neutralizing stomach acid.

  • H2 blockers: Medications like famotidine (Pepcid) reduce acid production and provide longer relief than antacids.

  • Proton pump inhibitors (PPIs): Stronger acid blockers like omeprazole (Prilosec), lansoprazole (Prevacid), and esomeprazole (Nexium) block acid production and allow the esophageal tissue to heal. They are available both over-the-counter and in prescription strength. 

Surgical procedures:

For severe GERD that doesn't respond to medication or lifestyle changes, a doctor may recommend surgery to strengthen the lower esophageal sphincter. 

  • Nissen fundoplication: This procedure involves wrapping the upper part of the stomach around the lower esophagus to reinforce the sphincter.

  • LINX device: A ring of magnetic beads is surgically placed around the junction of the stomach and esophagus to keep it closed against reflux


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